Modular UBE2H-CTLH E2-E3 complexes regulate erythroid maturation
Modular UBE2H-CTLH E2-E3 complexes regulate erythroid maturation
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Sherpa, Dawafuti , Mueller, Judith , Karayel, Özge , Xu, Peng , Yao, Yu , Chrustowicz, Jakub , Gottemukkala, Karthik V , Baumann, Christine , Gross, Annette , Czarnecki, Oliver , Zhang, Wei , Gu, Jun , Nilvebrant, Johan , Sidhu, Sachdev S , Murray, Peter J , Mann, Matthias , Weiss, Mitchell J , Schulman, Brenda A and Alpi, Arno F
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England: eLife Sciences Publications Ltd
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English
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England: eLife Sciences Publications Ltd
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The development of haematopoietic stem cells into mature erythrocytes - erythropoiesis - is a controlled process characterized by cellular reorganization and drastic reshaping of the proteome landscape. Failure of ordered erythropoiesis is associated with anaemias and haematological malignancies. Although the ubiquitin system is a known crucial pos...
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Modular UBE2H-CTLH E2-E3 complexes regulate erythroid maturation
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TN_cdi_doaj_primary_oai_doaj_org_article_34cf5cd0625f4e91870c6fb2f280211e
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_34cf5cd0625f4e91870c6fb2f280211e
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.77937