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IceR improves proteome coverage and data completeness in global and single-cell proteomics

IceR improves proteome coverage and data completeness in global and single-cell proteomics

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_351845f950f84ca38cb5bf54177b0ef5

IceR improves proteome coverage and data completeness in global and single-cell proteomics

About this item

Full title

IceR improves proteome coverage and data completeness in global and single-cell proteomics

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2021-08, Vol.12 (1), p.4787-4787, Article 4787

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Label-free proteomics by data-dependent acquisition enables the unbiased quantification of thousands of proteins, however it notoriously suffers from high rates of missing values, thus prohibiting consistent protein quantification across large sample cohorts. To solve this, we here present IceR (Ion current extraction Re-quantification), an efficie...

Alternative Titles

Full title

IceR improves proteome coverage and data completeness in global and single-cell proteomics

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_351845f950f84ca38cb5bf54177b0ef5

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_351845f950f84ca38cb5bf54177b0ef5

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-021-25077-6

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