The complement C3-complement factor D-C3a receptor signalling axis regulates cardiac remodelling in...
The complement C3-complement factor D-C3a receptor signalling axis regulates cardiac remodelling in right ventricular failure
About this item
Full title
Author / Creator
Ito, Shogo , Hashimoto, Hisayuki , Yamakawa, Hiroyuki , Kusumoto, Dai , Akiba, Yohei , Nakamura, Takahiro , Momoi, Mizuki , Komuro, Jin , Katsuki, Toshiomi , Kimura, Mai , Kishino, Yoshikazu , Kashimura, Shin , Kunitomi, Akira , Lachmann, Mark , Shimojima, Masaya , Yozu, Gakuto , Motoda, Chikaaki , Seki, Tomohisa , Yamamoto, Tsunehisa , Shinya, Yoshiki , Hiraide, Takahiro , Kataoka, Masaharu , Kawakami, Takashi , Suzuki, Kunimichi , Ito, Kei , Yada, Hirotaka , Abe, Manabu , Osaka, Mizuko , Tsuru, Hiromi , Yoshida, Masayuki , Sakimura, Kenji , Fukumoto, Yoshihiro , Yuzaki, Michisuke , Fukuda, Keiichi and Yuasa, Shinsuke
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Failure of the right ventricle plays a critical role in any type of heart failure. However, the mechanism remains unclear, and there is no specific therapy. Here, we show that the right ventricle predominantly expresses alternative complement pathway-related genes, including
Cfd
and
C3aR1
. Complement 3 (
C3
)-knockout attenuates...
Alternative Titles
Full title
The complement C3-complement factor D-C3a receptor signalling axis regulates cardiac remodelling in right ventricular failure
Authors, Artists and Contributors
Author / Creator
Hashimoto, Hisayuki
Yamakawa, Hiroyuki
Kusumoto, Dai
Akiba, Yohei
Nakamura, Takahiro
Momoi, Mizuki
Komuro, Jin
Katsuki, Toshiomi
Kimura, Mai
Kishino, Yoshikazu
Kashimura, Shin
Kunitomi, Akira
Lachmann, Mark
Shimojima, Masaya
Yozu, Gakuto
Motoda, Chikaaki
Seki, Tomohisa
Yamamoto, Tsunehisa
Shinya, Yoshiki
Hiraide, Takahiro
Kataoka, Masaharu
Kawakami, Takashi
Suzuki, Kunimichi
Ito, Kei
Yada, Hirotaka
Abe, Manabu
Osaka, Mizuko
Tsuru, Hiromi
Yoshida, Masayuki
Sakimura, Kenji
Fukumoto, Yoshihiro
Yuzaki, Michisuke
Fukuda, Keiichi
Yuasa, Shinsuke
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_3560dce292e7450caafa24bebf469864
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3560dce292e7450caafa24bebf469864
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-33152-9
