MITF activity is regulated by a direct interaction with RAF proteins in melanoma cells
MITF activity is regulated by a direct interaction with RAF proteins in melanoma cells
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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The MITF transcription factor and the RAS/RAF/MEK/ERK pathway are two interconnected main players in melanoma. Understanding how MITF activity is regulated represents a key question since its dynamic modulation is involved in the phenotypic plasticity of melanoma cells and their resistance to therapy. By investigating the role of ARAF in NRAS-drive...
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MITF activity is regulated by a direct interaction with RAF proteins in melanoma cells
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TN_cdi_doaj_primary_oai_doaj_org_article_3576fa81d3bb4cd3b9c8215dfe4686e5
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3576fa81d3bb4cd3b9c8215dfe4686e5
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ISSN
2399-3642
E-ISSN
2399-3642
DOI
10.1038/s42003-022-03049-w
