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Impact of Notch3 Activation on Aortic Aneurysm Development in Marfan Syndrome

Impact of Notch3 Activation on Aortic Aneurysm Development in Marfan Syndrome

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_35b0749cb78247e98cfac514fcd25903

Impact of Notch3 Activation on Aortic Aneurysm Development in Marfan Syndrome

About this item

Full title

Impact of Notch3 Activation on Aortic Aneurysm Development in Marfan Syndrome

Publisher

Egypt: Hindawi

Journal title

Journal of immunology research, 2022-02, Vol.2022, p.1-11

Language

English

Formats

Publication information

Publisher

Egypt: Hindawi

More information

Scope and Contents

Contents

Background. The leading cause of mortality in patients with Marfan syndrome (MFS) is thoracic aortic aneurysm and dissection. Notch signaling is essential for vessel morphogenesis and function. However, the role of Notch signaling in aortic pathology and aortic smooth muscle cell (SMC) differentiation in Marfan syndrome (MFS) is not completely unde...

Alternative Titles

Full title

Impact of Notch3 Activation on Aortic Aneurysm Development in Marfan Syndrome

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_35b0749cb78247e98cfac514fcd25903

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_35b0749cb78247e98cfac514fcd25903

Other Identifiers

ISSN

2314-8861

E-ISSN

2314-7156

DOI

10.1155/2022/7538649

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