Genetic evidence from Mendelian randomization links CD40 levels to increased risk of estrogen recept...
Genetic evidence from Mendelian randomization links CD40 levels to increased risk of estrogen receptor-positive breast cancer
About this item
Full title
Author / Creator
Yi, Junyu , Chen, Qingfeng , Liu, Xiaoyi , Mao, Yan , Wang, Yongmei , Lv, Meng , Wang, Haibo and Wang, Yuanyuan
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
This study uses Mendelian randomization (MR) to investigate the causal roles of CD40 and CD40L in BC.Data from genome-wide association studies (GWAS) on BC (overall, ER-positive, and ER-negative subtypes) and CD40/CD40L levels were obtained from the IEU database. Causal associations were assessed using the inverse-variance weighted (IVW) method, wi...
Alternative Titles
Full title
Genetic evidence from Mendelian randomization links CD40 levels to increased risk of estrogen receptor-positive breast cancer
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_35b125d5aa3840d9aa7dbbf6b1444c87
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_35b125d5aa3840d9aa7dbbf6b1444c87
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-025-99410-0
