Histone Variant H3.3 Mutations in Defining the Chromatin Function in Mammals
Histone Variant H3.3 Mutations in Defining the Chromatin Function in Mammals
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Switzerland: MDPI AG
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English
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Switzerland: MDPI AG
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The systematic mutation of histone 3 (H3) genes in model organisms has proven to be a valuable tool to distinguish the functional role of histone residues. No system exists in mammalian cells to directly manipulate canonical histone H3 due to a large number of clustered and multi-loci histone genes. Over the years, oncogenic histone mutations in a...
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Histone Variant H3.3 Mutations in Defining the Chromatin Function in Mammals
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TN_cdi_doaj_primary_oai_doaj_org_article_35b6958f90294fd9892900915af357c8
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_35b6958f90294fd9892900915af357c8
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ISSN
2073-4409
E-ISSN
2073-4409
DOI
10.3390/cells9122716