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Histone Variant H3.3 Mutations in Defining the Chromatin Function in Mammals

Histone Variant H3.3 Mutations in Defining the Chromatin Function in Mammals

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_35b6958f90294fd9892900915af357c8

Histone Variant H3.3 Mutations in Defining the Chromatin Function in Mammals

About this item

Full title

Histone Variant H3.3 Mutations in Defining the Chromatin Function in Mammals

Publisher

Switzerland: MDPI AG

Journal title

Cells (Basel, Switzerland), 2020-12, Vol.9 (12), p.2716

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

The systematic mutation of histone 3 (H3) genes in model organisms has proven to be a valuable tool to distinguish the functional role of histone residues. No system exists in mammalian cells to directly manipulate canonical histone H3 due to a large number of clustered and multi-loci histone genes. Over the years, oncogenic histone mutations in a...

Alternative Titles

Full title

Histone Variant H3.3 Mutations in Defining the Chromatin Function in Mammals

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_35b6958f90294fd9892900915af357c8

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_35b6958f90294fd9892900915af357c8

Other Identifiers

ISSN

2073-4409

E-ISSN

2073-4409

DOI

10.3390/cells9122716

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