Reactive astrocytes acquire neuroprotective as well as deleterious signatures in response to Tau and...
Reactive astrocytes acquire neuroprotective as well as deleterious signatures in response to Tau and Aß pathology
About this item
Full title
Author / Creator
Jiwaji, Zoeb , Tiwari, Sachin S. , Avilés-Reyes, Rolando X. , Hooley, Monique , Hampton, David , Torvell, Megan , Johnson, Delinda A. , McQueen, Jamie , Baxter, Paul , Sabari-Sankar, Kayalvizhi , Qiu, Jing , He, Xin , Fowler, Jill , Febery, James , Gregory, Jenna , Rose, Jamie , Tulloch, Jane , Loan, Jamie , Story, David , McDade, Karina , Smith, Amy M. , Greer, Peta , Ball, Matthew , Kind, Peter C. , Matthews, Paul M. , Smith, Colin , Dando, Owen , Spires-Jones, Tara L. , Johnson, Jeffrey A. , Chandran, Siddharthan and Hardingham, Giles E.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Alzheimer’s disease (AD) alters astrocytes, but the effect of Aß and Tau pathology is poorly understood. TRAP-seq translatome analysis of astrocytes in APP/PS1 ß-amyloidopathy and MAPT
P301S
tauopathy mice revealed that only Aß influenced expression of AD risk genes, but both pathologies precociously induced age-dependent changes, and had dis...
Alternative Titles
Full title
Reactive astrocytes acquire neuroprotective as well as deleterious signatures in response to Tau and Aß pathology
Authors, Artists and Contributors
Author / Creator
Tiwari, Sachin S.
Avilés-Reyes, Rolando X.
Hooley, Monique
Hampton, David
Torvell, Megan
Johnson, Delinda A.
McQueen, Jamie
Baxter, Paul
Sabari-Sankar, Kayalvizhi
Qiu, Jing
He, Xin
Fowler, Jill
Febery, James
Gregory, Jenna
Rose, Jamie
Tulloch, Jane
Loan, Jamie
Story, David
McDade, Karina
Smith, Amy M.
Greer, Peta
Ball, Matthew
Kind, Peter C.
Matthews, Paul M.
Smith, Colin
Dando, Owen
Spires-Jones, Tara L.
Johnson, Jeffrey A.
Chandran, Siddharthan
Hardingham, Giles E.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_3684566e972d48bda37be69378c00e42
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3684566e972d48bda37be69378c00e42
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-27702-w
