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Tamoxifen decreases ovarian toxicity without compromising cancer treatment in a rat model of mammary...

Tamoxifen decreases ovarian toxicity without compromising cancer treatment in a rat model of mammary...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_36bedf37600448b6a8744706a443fbb9

Tamoxifen decreases ovarian toxicity without compromising cancer treatment in a rat model of mammary cancer

About this item

Full title

Tamoxifen decreases ovarian toxicity without compromising cancer treatment in a rat model of mammary cancer

Publisher

England: BioMed Central Ltd

Journal title

BMC genomics, 2023-06, Vol.24 (1), p.325-15, Article 325

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Premenopausal women diagnosed with breast cancer often face aggressive chemotherapy resulting in infertility. Tamoxifen (TAM) is a selective estrogen receptor modulator that was previously suggested as a protective agent against chemotherapy-induced ovarian failure. In the current study, we examined mechanisms of the protective action of TAM in the...

Alternative Titles

Full title

Tamoxifen decreases ovarian toxicity without compromising cancer treatment in a rat model of mammary cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_36bedf37600448b6a8744706a443fbb9

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_36bedf37600448b6a8744706a443fbb9

Other Identifiers

ISSN

1471-2164

E-ISSN

1471-2164

DOI

10.1186/s12864-023-09423-0

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