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Genetic associations of plasma metabolites with immune cells in hyperthyroidism revealed by Mendelia...

Genetic associations of plasma metabolites with immune cells in hyperthyroidism revealed by Mendelia...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_36cc77f81bd0466790ff8d660f4825c3

Genetic associations of plasma metabolites with immune cells in hyperthyroidism revealed by Mendelian randomization and GWAS-sc-eQTLs xQTLbiolinks analysis

About this item

Full title

Genetic associations of plasma metabolites with immune cells in hyperthyroidism revealed by Mendelian randomization and GWAS-sc-eQTLs xQTLbiolinks analysis

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2025-01, Vol.15 (1), p.1377-15, Article 1377

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Mendelian randomization (MR) was employed to investigate the causal relationships between immune cell phenotypes, hyperthyroidism (HD), and potential metabolic mediators. In this study, we acquired 731 immune cell phenotypes from genome-wide association studies (GWAS) (
n
 = 18,622), HD data from the research by Handan Melike Dönertaş et al....

Alternative Titles

Full title

Genetic associations of plasma metabolites with immune cells in hyperthyroidism revealed by Mendelian randomization and GWAS-sc-eQTLs xQTLbiolinks analysis

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_36cc77f81bd0466790ff8d660f4825c3

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_36cc77f81bd0466790ff8d660f4825c3

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-025-85664-1

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