APOE2: protective mechanism and therapeutic implications for Alzheimer’s disease
APOE2: protective mechanism and therapeutic implications for Alzheimer’s disease
About this item
Full title
Author / Creator
Publisher
England: BioMed Central Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: BioMed Central Ltd
Subjects
More information
Scope and Contents
Contents
Investigations of apolipoprotein E (
APOE
) gene, the major genetic risk modifier for Alzheimer’s disease (AD), have yielded significant insights into the pathogenic mechanism. Among the three common coding variants,
APOE*ε4
increases, whereas
APOE*ε2
decreases the risk of late-onset AD compared with
APOE*ε3
. Despite increa...
Alternative Titles
Full title
APOE2: protective mechanism and therapeutic implications for Alzheimer’s disease
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_36de4881a3f6494a83af09590ed383ae
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_36de4881a3f6494a83af09590ed383ae
Other Identifiers
ISSN
1750-1326
E-ISSN
1750-1326
DOI
10.1186/s13024-020-00413-4
