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Surfactant protein D alleviates chondrocytes senescence by upregulating SIRT3/SOD2 pathway in osteoa...

Surfactant protein D alleviates chondrocytes senescence by upregulating SIRT3/SOD2 pathway in osteoa...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_36e0742457264c4281287d38c2ceaf56

Surfactant protein D alleviates chondrocytes senescence by upregulating SIRT3/SOD2 pathway in osteoarthritis

About this item

Full title

Surfactant protein D alleviates chondrocytes senescence by upregulating SIRT3/SOD2 pathway in osteoarthritis

Publisher

England: Springer

Journal title

Molecular Medicine, 2025-04, Vol.31 (1), p.161-17, Article 161

Language

English

Formats

Publication information

Publisher

England: Springer

More information

Scope and Contents

Contents

Osteoarthritis (OA) is an age-related degenerative disease that affects bones and joints. The hallmark pathogenesis of OA is associated with chondrocyte senescence. Surfactant protein D (SP-D) is a member of the innate immune proteins family, which can inhibit the immune inflammatory response of chondrocytes. However, the effect of SP-D on chondroc...

Alternative Titles

Full title

Surfactant protein D alleviates chondrocytes senescence by upregulating SIRT3/SOD2 pathway in osteoarthritis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_36e0742457264c4281287d38c2ceaf56

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_36e0742457264c4281287d38c2ceaf56

Other Identifiers

ISSN

1528-3658,1076-1551

E-ISSN

1528-3658

DOI

10.1186/s10020-025-01221-6

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