Detection of genetic variation and base modifications at base-pair resolution on both DNA and RNA
Detection of genetic variation and base modifications at base-pair resolution on both DNA and RNA
About this item
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Author / Creator
Wang, Zhen , Maluenda, Jérôme , Giraut, Laurène , Vieille, Thibault , Lefevre, Andréas , Salthouse, David , Radou, Gaël , Moulinas, Rémi , Astete, Sandra , D’Avezac, Pol , Smith, Geoff , André, Charles , Allemand, Jean-François , Bensimon, David , Croquette, Vincent , Ouellet, Jimmy and Hamilton, Gordon
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Accurate decoding of nucleic acid variation is critical to understand the complexity and regulation of genome function. Here we use a single-molecule magnetic tweezer (MT) platform to identify sequence variation and map a range of important epigenetic base modifications with high sensitivity, specificity, and precision in the same single molecules...
Alternative Titles
Full title
Detection of genetic variation and base modifications at base-pair resolution on both DNA and RNA
Authors, Artists and Contributors
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_36f2d6c25b90460cab0986d3713e402b
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_36f2d6c25b90460cab0986d3713e402b
Other Identifiers
ISSN
2399-3642
E-ISSN
2399-3642
DOI
10.1038/s42003-021-01648-7
