Restoration of the molecular clock is tumor suppressive in neuroblastoma
Restoration of the molecular clock is tumor suppressive in neuroblastoma
About this item
Full title
Author / Creator
Moreno-Smith, Myrthala , Milazzo, Giorgio , Tao, Ling , Fekry, Baharan , Zhu, Bokai , Mohammad, Mahmoud A. , Di Giacomo, Simone , Borkar, Roshan , Reddy, Karthik Reddy Kami , Capasso, Mario , Vasudevan, Sanjeev A. , Sumazin, Pavel , Hicks, John , Putluri, Nagireddy , Perini, Giovanni , Eckel-Mahan, Kristin , Burris, Thomas P. and Barbieri, Eveline
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
MYCN activation is a hallmark of advanced neuroblastoma (NB) and a known master regulator of metabolic reprogramming, favoring NB adaptation to its microenvironment. We found that the expression of the main regulators of the molecular clock loops is profoundly disrupted in MYCN-amplified NB patients, and this disruption independently predicts poor...
Alternative Titles
Full title
Restoration of the molecular clock is tumor suppressive in neuroblastoma
Authors, Artists and Contributors
Author / Creator
Milazzo, Giorgio
Tao, Ling
Fekry, Baharan
Zhu, Bokai
Mohammad, Mahmoud A.
Di Giacomo, Simone
Borkar, Roshan
Reddy, Karthik Reddy Kami
Capasso, Mario
Vasudevan, Sanjeev A.
Sumazin, Pavel
Hicks, John
Putluri, Nagireddy
Perini, Giovanni
Eckel-Mahan, Kristin
Burris, Thomas P.
Barbieri, Eveline
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_36f78ce6f76041c49c8161f0733a70f4
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_36f78ce6f76041c49c8161f0733a70f4
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-24196-4
