The interplay between IGF-1R signaling and Hippo-YAP in breast cancer stem cells
The interplay between IGF-1R signaling and Hippo-YAP in breast cancer stem cells
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Publisher
England: BioMed Central
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Language
English
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Publisher
England: BioMed Central
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Contents
Both IGF-1R/PI3K/AKT/mTOR and Hippo pathways are crucial for breast cancer stem cells (BCSCs). However, their interplay remains unclear.
Four triple negative breast cancer cell lines derived from CSC of two patient-derived xenografts (PDXs), AS-B145, AS-B145-1R, AS-B244, and AS-B244-1R, were used to elucidate the role of YAP in BCSCs. YAP silenc...
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Full title
The interplay between IGF-1R signaling and Hippo-YAP in breast cancer stem cells
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TN_cdi_doaj_primary_oai_doaj_org_article_3702ffa228b14b1f956296633f4eb40c
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3702ffa228b14b1f956296633f4eb40c
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ISSN
1478-811X
E-ISSN
1478-811X
DOI
10.1186/s12964-023-01088-2
