A tetravalent live attenuated dengue virus vaccine stimulates balanced immunity to multiple serotype...
A tetravalent live attenuated dengue virus vaccine stimulates balanced immunity to multiple serotypes in humans
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
The four-dengue virus (DENV) serotypes infect several hundred million people annually. For the greatest safety and efficacy, tetravalent DENV vaccines are designed to stimulate balanced protective immunity to all four serotypes. However, this has been difficult to achieve. Clinical trials with a leading vaccine demonstrated that unbalanced replicat...
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A tetravalent live attenuated dengue virus vaccine stimulates balanced immunity to multiple serotypes in humans
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TN_cdi_doaj_primary_oai_doaj_org_article_3754cf1077b043a0a2eef363edc7666d
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3754cf1077b043a0a2eef363edc7666d
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-21384-0
