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WTAP-mediated N 6-methyladenosine modification of NLRP3 mRNA in kidney injury of diabetic nephropath...

WTAP-mediated N 6-methyladenosine modification of NLRP3 mRNA in kidney injury of diabetic nephropath...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_376980f43a514588888631d3a2271fa1

WTAP-mediated N 6-methyladenosine modification of NLRP3 mRNA in kidney injury of diabetic nephropathy

About this item

Full title

WTAP-mediated N 6-methyladenosine modification of NLRP3 mRNA in kidney injury of diabetic nephropathy

Publisher

BMC

Journal title

Cellular & molecular biology letters, 2022-12, Vol.27 (1), p.1-21

Language

English

Formats

Publication information

Publisher

BMC

More information

Scope and Contents

Contents

Abstract Background Diabetic nephropathy (DN) is prevalent in patients with diabetes. N 6-methyladenosine (m6A) methylation has been found to cause modification of nucleotide-binding oligomerization domain, leucine-rich repeat, and pyrin domain-containing (NLRP) 3, which is involved in cell pyroptosis and inflammation. WTAP is a key gene in modulat...

Alternative Titles

Full title

WTAP-mediated N 6-methyladenosine modification of NLRP3 mRNA in kidney injury of diabetic nephropathy

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_376980f43a514588888631d3a2271fa1

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_376980f43a514588888631d3a2271fa1

Other Identifiers

ISSN

1425-8153

E-ISSN

1689-1392

DOI

10.1186/s11658-022-00350-8

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