Adenylate kinase 4 modulates oxidative stress and stabilizes HIF-1α to drive lung adenocarcinoma met...
Adenylate kinase 4 modulates oxidative stress and stabilizes HIF-1α to drive lung adenocarcinoma metastasis
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Publisher
England: BioMed Central
Journal title
Language
English
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Publisher
England: BioMed Central
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Contents
Adenylate kinase 4 (AK4) has been identified as a biomarker of metastasis in lung cancer. However, the impacts of AK4 on metabolic genes and its translational value for drug repositioning remain unclear.
Ingenuity upstream analyses were used to identify potential transcription factors that regulate the AK4 metabolic gene signature. The expressio...
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Full title
Adenylate kinase 4 modulates oxidative stress and stabilizes HIF-1α to drive lung adenocarcinoma metastasis
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TN_cdi_doaj_primary_oai_doaj_org_article_37770badd54248a69387cbc83ac3866d
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_37770badd54248a69387cbc83ac3866d
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ISSN
1756-8722
E-ISSN
1756-8722
DOI
10.1186/s13045-019-0698-5
