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WIF-1 contributes to lupus-induced neuropsychological deficits via the CRYAB/STAT4-SHH axis

WIF-1 contributes to lupus-induced neuropsychological deficits via the CRYAB/STAT4-SHH axis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_379656e75aa446f5b544b39a683e0406

WIF-1 contributes to lupus-induced neuropsychological deficits via the CRYAB/STAT4-SHH axis

About this item

Full title

WIF-1 contributes to lupus-induced neuropsychological deficits via the CRYAB/STAT4-SHH axis

Publisher

England: BioMed Central Ltd

Journal title

Arthritis research & therapy, 2024-10, Vol.26 (1), p.183-20, Article 183

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Neuropsychiatric systemic lupus erythematosus (NPSLE) often manifests as cognitive deterioration, with activated microglia and blood-brain barrier (BBB) disruption implicated in these neurological complications. Wnt-inhibitory factor-1 (WIF-1), a secreted protein, has been detected in the cerebrospinal fluid (CSF) of NPSLE patients. However, the co...

Alternative Titles

Full title

WIF-1 contributes to lupus-induced neuropsychological deficits via the CRYAB/STAT4-SHH axis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_379656e75aa446f5b544b39a683e0406

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_379656e75aa446f5b544b39a683e0406

Other Identifiers

ISSN

1478-6362,1478-6354

E-ISSN

1478-6362

DOI

10.1186/s13075-024-03420-8

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