WIF-1 contributes to lupus-induced neuropsychological deficits via the CRYAB/STAT4-SHH axis
WIF-1 contributes to lupus-induced neuropsychological deficits via the CRYAB/STAT4-SHH axis
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Author / Creator
Tan, Liping , Fan, Yu , Xu, Xinyi , Zhang, Tianshu , Cao, Xiangyu , Zhang, Chenghao , Liang, Jun , Hou, Yayi and Dou, Huan
Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Neuropsychiatric systemic lupus erythematosus (NPSLE) often manifests as cognitive deterioration, with activated microglia and blood-brain barrier (BBB) disruption implicated in these neurological complications. Wnt-inhibitory factor-1 (WIF-1), a secreted protein, has been detected in the cerebrospinal fluid (CSF) of NPSLE patients. However, the co...
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Full title
WIF-1 contributes to lupus-induced neuropsychological deficits via the CRYAB/STAT4-SHH axis
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TN_cdi_doaj_primary_oai_doaj_org_article_379656e75aa446f5b544b39a683e0406
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_379656e75aa446f5b544b39a683e0406
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ISSN
1478-6362,1478-6354
E-ISSN
1478-6362
DOI
10.1186/s13075-024-03420-8