Transcriptional regulatory networks underlying gene expression changes in Huntington's disease
Transcriptional regulatory networks underlying gene expression changes in Huntington's disease
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Transcriptional changes occur presymptomatically and throughout Huntington's disease (HD), motivating the study of transcriptional regulatory networks (TRNs) in HD. We reconstructed a genome‐scale model for the target genes of 718 transcription factors (TFs) in the mouse striatum by integrating a model of genomic binding sites with transcriptome pr...
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Transcriptional regulatory networks underlying gene expression changes in Huntington's disease
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TN_cdi_doaj_primary_oai_doaj_org_article_37a0a3de07ca4d86ab89638ff4d313a8
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_37a0a3de07ca4d86ab89638ff4d313a8
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ISSN
1744-4292
E-ISSN
1744-4292
DOI
10.15252/msb.20167435
