Synthetic Diphenylacetylene-Based Retinoids Induce DNA Damage in Chinese Hamster Ovary Cells without...
Synthetic Diphenylacetylene-Based Retinoids Induce DNA Damage in Chinese Hamster Ovary Cells without Altering Viability
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Publisher
Switzerland: MDPI AG
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Language
English
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Switzerland: MDPI AG
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All-trans-retinoic acid (ATRA), the active metabolite of vitamin A, plays a pivotal role in cell differentiation, proliferation and embryonic development. It is an effective therapy for dermatological disorders and malignancies. ATRA is prone to isomerization and oxidation, which can affect its activity and selectivity. Novel diphenylacetylene-base...
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Synthetic Diphenylacetylene-Based Retinoids Induce DNA Damage in Chinese Hamster Ovary Cells without Altering Viability
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TN_cdi_doaj_primary_oai_doaj_org_article_38304852a28944ae847afdc1b5759ca1
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_38304852a28944ae847afdc1b5759ca1
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ISSN
1420-3049
E-ISSN
1420-3049
DOI
10.3390/molecules27030977
