Distinct SoxB1 networks are required for naïve and primed pluripotency
Distinct SoxB1 networks are required for naïve and primed pluripotency
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England: eLife Sciences Publications Ltd
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English
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Publisher
England: eLife Sciences Publications Ltd
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Deletion of Sox2 from mouse embryonic stem cells (ESCs) causes trophectodermal differentiation. While this can be prevented by enforced expression of the related SOXB1 proteins, SOX1 or SOX3, the roles of SOXB1 proteins in epiblast stem cell (EpiSC) pluripotency are unknown. Here, we show that Sox2 can be deleted from EpiSCs with impunity. This is...
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Distinct SoxB1 networks are required for naïve and primed pluripotency
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TN_cdi_doaj_primary_oai_doaj_org_article_383310e3d27d44c8aad4b1b095ff1014
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_383310e3d27d44c8aad4b1b095ff1014
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.27746
