VAV2 signaling promotes regenerative proliferation in both cutaneous and head and neck squamous cell...
VAV2 signaling promotes regenerative proliferation in both cutaneous and head and neck squamous cell carcinoma
About this item
Full title
Author / Creator
Lorenzo-Martín, L. Francisco , Fernández-Parejo, Natalia , Menacho-Márquez, Mauricio , Rodríguez-Fdez, Sonia , Robles-Valero, Javier , Zumalave, Sonia , Fabbiano, Salvatore , Pascual, Gloria , García-Pedrero, Juana M. , Abad, Antonio , García-Macías, María C. , González, Nazareno , Lorenzano-Menna, Pablo , Pavón, Miguel A. , González-Sarmiento, Rogelio , Segrelles, Carmen , Paramio, Jesús M. , Tubío, José M. C. , Rodrigo, Juan P. , Benitah, Salvador A. , Cuadrado, Myriam and Bustelo, Xosé R.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Regenerative proliferation capacity and poor differentiation are histological features usually linked to poor prognosis in head and neck squamous cell carcinoma (hnSCC). However, the pathways that regulate them remain ill-characterized. Here, we show that those traits can be triggered by the RHO GTPase activator VAV2 in keratinocytes present in the...
Alternative Titles
Full title
VAV2 signaling promotes regenerative proliferation in both cutaneous and head and neck squamous cell carcinoma
Authors, Artists and Contributors
Author / Creator
Fernández-Parejo, Natalia
Menacho-Márquez, Mauricio
Rodríguez-Fdez, Sonia
Robles-Valero, Javier
Zumalave, Sonia
Fabbiano, Salvatore
Pascual, Gloria
García-Pedrero, Juana M.
Abad, Antonio
García-Macías, María C.
González, Nazareno
Lorenzano-Menna, Pablo
Pavón, Miguel A.
González-Sarmiento, Rogelio
Segrelles, Carmen
Paramio, Jesús M.
Tubío, José M. C.
Rodrigo, Juan P.
Benitah, Salvador A.
Cuadrado, Myriam
Bustelo, Xosé R.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_383992e6d52c41ef94a9df8bb7b4e08c
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_383992e6d52c41ef94a9df8bb7b4e08c
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-18524-3
