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Antitumor efficacy of 90Y-NM600 targeted radionuclide therapy and PD-1 blockade is limited by regula...

Antitumor efficacy of 90Y-NM600 targeted radionuclide therapy and PD-1 blockade is limited by regula...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_385680f3c7034b26aee4d0c6c0c3d464

Antitumor efficacy of 90Y-NM600 targeted radionuclide therapy and PD-1 blockade is limited by regulatory T cells in murine prostate tumors

About this item

Full title

Antitumor efficacy of 90Y-NM600 targeted radionuclide therapy and PD-1 blockade is limited by regulatory T cells in murine prostate tumors

Publisher

London: BMJ Publishing Group Ltd

Journal title

Journal for immunotherapy of cancer, 2022-08, Vol.10 (8), p.e005060

Language

English

Formats

Publication information

Publisher

London: BMJ Publishing Group Ltd

More information

Scope and Contents

Contents

BackgroundSystemic radiation treatments that preferentially irradiate cancer cells over normal tissue, known as targeted radionuclide therapy (TRT), have shown significant potential for treating metastatic prostate cancer. Preclinical studies have demonstrated the ability of external beam radiation therapy (EBRT) to sensitize tumors to T cell check...

Alternative Titles

Full title

Antitumor efficacy of 90Y-NM600 targeted radionuclide therapy and PD-1 blockade is limited by regulatory T cells in murine prostate tumors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_385680f3c7034b26aee4d0c6c0c3d464

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_385680f3c7034b26aee4d0c6c0c3d464

Other Identifiers

E-ISSN

2051-1426

DOI

10.1136/jitc-2022-005060

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