Inhibition of fatty acid synthase protects obese mice from acute lung injury via ameliorating lung e...
Inhibition of fatty acid synthase protects obese mice from acute lung injury via ameliorating lung endothelial dysfunction
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Author / Creator
Wu, Zhuhua , Zhu, Li , Nie, Xinran , Liu, Yingli , Zhang, Xiaoju and Qi, Yong
Publisher
England: BioMed Central Ltd
Journal title
Language
English
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Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
Obesity has been identified as a risk factor for acute lung injury/acute respiratory distress syndrome (ALI/ARDS). However, the underlying mechanisms remain elusive. This study aimed to investigate the role of fatty acid synthase (FASN) in lipopolysaccharide (LPS)-induced ALI under obesity.
A high-fat diet-induced obese (DIO) mouse model was est...
Alternative Titles
Full title
Inhibition of fatty acid synthase protects obese mice from acute lung injury via ameliorating lung endothelial dysfunction
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Author / Creator
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_38962a313bc844d98f92cc573d5d7661
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_38962a313bc844d98f92cc573d5d7661
Other Identifiers
ISSN
1465-993X,1465-9921
E-ISSN
1465-993X,1465-9921
DOI
10.1186/s12931-023-02382-w
