Loss of anticodon wobble uridine modifications affects tRNA(Lys) function and protein levels in Sacc...
Loss of anticodon wobble uridine modifications affects tRNA(Lys) function and protein levels in Saccharomyces cerevisiae
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United States: Public Library of Science (PLoS)
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English
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United States: Public Library of Science (PLoS)
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In eukaryotes, wobble uridines in the anticodons of tRNA(Lys)UUU, tRNA(Glu)UUC and tRNA(Gln)UUG are modified to 5-methoxy-carbonyl-methyl-2-thio-uridine (mcm5s2U). While mutations in subunits of the Elongator complex (Elp1-Elp6), which disable mcm5 side chain formation, or removal of components of the thiolation pathway (Ncs2/Ncs6, Urm1, Uba4) are...
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Loss of anticodon wobble uridine modifications affects tRNA(Lys) function and protein levels in Saccharomyces cerevisiae
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TN_cdi_doaj_primary_oai_doaj_org_article_38b17139827c46c7a729aab3c6cdac6f
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_38b17139827c46c7a729aab3c6cdac6f
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E-ISSN
1932-6203
DOI
10.1371/journal.pone.0119261
