Integrative epigenomic and high-throughput functional enhancer profiling reveals determinants of enh...
Integrative epigenomic and high-throughput functional enhancer profiling reveals determinants of enhancer heterogeneity in gastric cancer
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Author / Creator
Sheng, Taotao , Ho, Shamaine Wei Ting , Ooi, Wen Fong , Xu, Chang , Xing, Manjie , Padmanabhan, Nisha , Huang, Kie Kyon , Ma, Lijia , Ray, Mohana , Guo, Yu Amanda , Sim, Ngak Leng , Anene-Nzelu, Chukwuemeka George , Chang, Mei Mei , Razavi-Mohseni, Milad , Beer, Michael A. , Foo, Roger Sik Yin , Sundar, Raghav , Chan, Yiong Huak , Tan, Angie Lay Keng , Ong, Xuewen , Skanderup, Anders Jacobsen , White, Kevin P. , Jha, Sudhakar and Tan, Patrick
Publisher
England: BioMed Central Ltd
Journal title
Language
English
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Publication information
Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
Enhancers are distal cis-regulatory elements required for cell-specific gene expression and cell fate determination. In cancer, enhancer variation has been proposed as a major cause of inter-patient heterogeneity-however, most predicted enhancer regions remain to be functionally tested.
We analyzed 132 epigenomic histone modification profiles of...
Alternative Titles
Full title
Integrative epigenomic and high-throughput functional enhancer profiling reveals determinants of enhancer heterogeneity in gastric cancer
Authors, Artists and Contributors
Author / Creator
Ho, Shamaine Wei Ting
Ooi, Wen Fong
Xu, Chang
Xing, Manjie
Padmanabhan, Nisha
Huang, Kie Kyon
Ma, Lijia
Ray, Mohana
Guo, Yu Amanda
Sim, Ngak Leng
Anene-Nzelu, Chukwuemeka George
Chang, Mei Mei
Razavi-Mohseni, Milad
Beer, Michael A.
Foo, Roger Sik Yin
Sundar, Raghav
Chan, Yiong Huak
Tan, Angie Lay Keng
Ong, Xuewen
Skanderup, Anders Jacobsen
White, Kevin P.
Jha, Sudhakar
Tan, Patrick
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_38cedd9ca8014168bc07ffb9aa64af83
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_38cedd9ca8014168bc07ffb9aa64af83
Other Identifiers
ISSN
1756-994X
E-ISSN
1756-994X
DOI
10.1186/s13073-021-00970-3