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Integrative epigenomic and high-throughput functional enhancer profiling reveals determinants of enh...

Integrative epigenomic and high-throughput functional enhancer profiling reveals determinants of enh...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_38cedd9ca8014168bc07ffb9aa64af83

Integrative epigenomic and high-throughput functional enhancer profiling reveals determinants of enhancer heterogeneity in gastric cancer

About this item

Full title

Integrative epigenomic and high-throughput functional enhancer profiling reveals determinants of enhancer heterogeneity in gastric cancer

Publisher

England: BioMed Central Ltd

Journal title

Genome medicine, 2021-10, Vol.13 (1), p.158-158, Article 158

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Enhancers are distal cis-regulatory elements required for cell-specific gene expression and cell fate determination. In cancer, enhancer variation has been proposed as a major cause of inter-patient heterogeneity-however, most predicted enhancer regions remain to be functionally tested.
We analyzed 132 epigenomic histone modification profiles of...

Alternative Titles

Full title

Integrative epigenomic and high-throughput functional enhancer profiling reveals determinants of enhancer heterogeneity in gastric cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_38cedd9ca8014168bc07ffb9aa64af83

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_38cedd9ca8014168bc07ffb9aa64af83

Other Identifiers

ISSN

1756-994X

E-ISSN

1756-994X

DOI

10.1186/s13073-021-00970-3

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