Genomic analysis of early-stage lung cancer reveals a role for TP53 mutations in distant metastasis
Genomic analysis of early-stage lung cancer reveals a role for TP53 mutations in distant metastasis
About this item
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Author / Creator
for the AACR Project GENIE Consortium represented by Shawn Sweeney , AACR Project GENIE Consortium represented by Shawn Sweeney , Van Egeren, Debra , Kohli, Khushi , Warner, Jeremy L. , Bedard, Philippe L. , Riely, Gregory , Lepisto, Eva , Schrag, Deborah , LeNoue-Newton, Michele , Catalano, Paul , Kehl, Kenneth L. and Michor, Franziska
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Patients with non-small cell lung cancer (NSCLC) who have distant metastases have a poor prognosis. To determine which genomic factors of the primary tumor are associated with metastasis, we analyzed data from 759 patients originally diagnosed with stage I–III NSCLC as part of the AACR Project GENIE Biopharma Collaborative consortium. We found that...
Alternative Titles
Full title
Genomic analysis of early-stage lung cancer reveals a role for TP53 mutations in distant metastasis
Authors, Artists and Contributors
Author / Creator
AACR Project GENIE Consortium represented by Shawn Sweeney
Van Egeren, Debra
Kohli, Khushi
Warner, Jeremy L.
Bedard, Philippe L.
Riely, Gregory
Lepisto, Eva
Schrag, Deborah
LeNoue-Newton, Michele
Catalano, Paul
Kehl, Kenneth L.
Michor, Franziska
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_38d145c0f30540fe966086128a46be62
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_38d145c0f30540fe966086128a46be62
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-022-21448-1
