Structure-mechanism-based engineering of chemical regulators targeting distinct pathological factors...
Structure-mechanism-based engineering of chemical regulators targeting distinct pathological factors in Alzheimer’s disease
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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The absence of effective therapeutics against Alzheimer’s disease (AD) is a result of the limited understanding of its multifaceted aetiology. Because of the lack of chemical tools to identify pathological factors, investigations into AD pathogenesis have also been insubstantial. Here we report chemical regulators that demonstrate distinct specific...
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Structure-mechanism-based engineering of chemical regulators targeting distinct pathological factors in Alzheimer’s disease
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TN_cdi_doaj_primary_oai_doaj_org_article_38e022ffa1474e819049faf03deff89d
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_38e022ffa1474e819049faf03deff89d
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms13115
