Clearance of peripheral nerve misfolded mutant protein by infiltrated macrophages correlates with mo...
Clearance of peripheral nerve misfolded mutant protein by infiltrated macrophages correlates with motor neuron disease progression
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Macrophages expressing C–C chemokine receptor type 2 (CCR2) infiltrate the central and peripheral neural tissues of amyotrophic lateral sclerosis (ALS) patients. To identify the functional role of CCR2
+
macrophages in the pathomechanisms of ALS, we used an ALS animal model,
mutant Cu/Zn superoxide dismutase 1
G93A
(
mSOD1
)-tr...
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Full title
Clearance of peripheral nerve misfolded mutant protein by infiltrated macrophages correlates with motor neuron disease progression
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TN_cdi_doaj_primary_oai_doaj_org_article_38e6c8f790e142f19d800032a48c1af0
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_38e6c8f790e142f19d800032a48c1af0
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-021-96064-6
