First-in-human trial of blood–brain barrier opening in amyotrophic lateral sclerosis using MR-guided...
First-in-human trial of blood–brain barrier opening in amyotrophic lateral sclerosis using MR-guided focused ultrasound
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
MR-guided focused ultrasound (MRgFUS) is an emerging technology that can accurately and transiently permeabilize the blood-brain barrier (BBB) for targeted drug delivery to the central nervous system. We conducted a single-arm, first-in-human trial to investigate the safety and feasibility of MRgFUS-induced BBB opening in eloquent primary motor cor...
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First-in-human trial of blood–brain barrier opening in amyotrophic lateral sclerosis using MR-guided focused ultrasound
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TN_cdi_doaj_primary_oai_doaj_org_article_39152bb20d4547b38efa39b5f3872500
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_39152bb20d4547b38efa39b5f3872500
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-12426-9