A RAB35-p85/PI3K axis controls oscillatory apical protrusions required for efficient chemotactic mig...
A RAB35-p85/PI3K axis controls oscillatory apical protrusions required for efficient chemotactic migration
About this item
Full title
Author / Creator
Corallino, Salvatore , Malinverno, Chiara , Neumann, Beate , Tischer, Christian , Palamidessi, Andrea , Frittoli, Emanuela , Panagiotakopoulou, Magdalini , Disanza, Andrea , Malet-Engra, Gema , Nastaly, Paulina , Galli, Camilla , Luise, Chiara , Bertalot, Giovanni , Pece, Salvatore , Di Fiore, Pier Paolo , Gauthier, Nils , Ferrari, Aldo , Maiuri, Paolo and Scita, Giorgio
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
How cells move chemotactically remains a major unmet challenge in cell biology. Emerging evidence indicates that for interpreting noisy, shallow gradients of soluble cues a system must behave as an excitable process. Here, through an RNAi-based, high-content screening approach, we identify RAB35 as necessary for the formation of growth factors (GFs...
Alternative Titles
Full title
A RAB35-p85/PI3K axis controls oscillatory apical protrusions required for efficient chemotactic migration
Authors, Artists and Contributors
Author / Creator
Malinverno, Chiara
Neumann, Beate
Tischer, Christian
Palamidessi, Andrea
Frittoli, Emanuela
Panagiotakopoulou, Magdalini
Disanza, Andrea
Malet-Engra, Gema
Nastaly, Paulina
Galli, Camilla
Luise, Chiara
Bertalot, Giovanni
Pece, Salvatore
Di Fiore, Pier Paolo
Gauthier, Nils
Ferrari, Aldo
Maiuri, Paolo
Scita, Giorgio
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_391b87a586fe4ec382591d31347a221d
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_391b87a586fe4ec382591d31347a221d
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-03571-8
