Cancer cell-intrinsic expression of MHC II in lung cancer cell lines is actively restricted by MEK/E...
Cancer cell-intrinsic expression of MHC II in lung cancer cell lines is actively restricted by MEK/ERK signaling and epigenetic mechanisms
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England: BMJ Publishing Group Ltd
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English
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England: BMJ Publishing Group Ltd
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BackgroundProgrammed death 1/programmed death ligand 1 (PD-1/PD-L1) targeted immunotherapy affords clinical benefit in ~20% of unselected patients with lung cancer. The factor(s) that determine whether a tumor responds or fails to respond to immunotherapy remains an active area of investigation. We have previously defined divergent responsiveness o...
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Cancer cell-intrinsic expression of MHC II in lung cancer cell lines is actively restricted by MEK/ERK signaling and epigenetic mechanisms
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TN_cdi_doaj_primary_oai_doaj_org_article_392478c81db649bab2de6e5e9eb696a8
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_392478c81db649bab2de6e5e9eb696a8
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ISSN
2051-1426
E-ISSN
2051-1426
DOI
10.1136/jitc-2019-000441
