Molecular Rationale behind the Differential Substrate Specificity of Bacterial RND Multi-Drug Transp...
Molecular Rationale behind the Differential Substrate Specificity of Bacterial RND Multi-Drug Transporters
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Resistance-Nodulation-cell Division (RND) transporters AcrB and AcrD of
Escherichia coli
expel a wide range of substrates out of the cell in conjunction with AcrA and TolC, contributing to the onset of bacterial multidrug resistance. Despite sharing an overall sequence identity of ~66% (similarity ~80%), these RND transporters feature distinc...
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Molecular Rationale behind the Differential Substrate Specificity of Bacterial RND Multi-Drug Transporters
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TN_cdi_doaj_primary_oai_doaj_org_article_392930ee1eca422298bd285496cace51
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_392930ee1eca422298bd285496cace51
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-017-08747-8
