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The Tumor Suppressor Par-4 Regulates Adipogenesis by Transcriptional Repression of PPARγ

The Tumor Suppressor Par-4 Regulates Adipogenesis by Transcriptional Repression of PPARγ

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_392f32452a5943538017099d1fe8b91c

The Tumor Suppressor Par-4 Regulates Adipogenesis by Transcriptional Repression of PPARγ

About this item

Full title

The Tumor Suppressor Par-4 Regulates Adipogenesis by Transcriptional Repression of PPARγ

Publisher

Switzerland: MDPI AG

Journal title

Cells (Basel, Switzerland), 2024-09, Vol.13 (17), p.1495

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

Prostate apoptosis response-4 (Par-4, also known as PAWR) is a ubiquitously expressed tumor suppressor protein that induces apoptosis selectively in cancer cells, while leaving normal cells unaffected. Our previous studies indicated that genetic loss of Par-4 promoted hepatic steatosis, adiposity, and insulin-resistance in chow-fed mice. Moreover,...

Alternative Titles

Full title

The Tumor Suppressor Par-4 Regulates Adipogenesis by Transcriptional Repression of PPARγ

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_392f32452a5943538017099d1fe8b91c

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_392f32452a5943538017099d1fe8b91c

Other Identifiers

ISSN

2073-4409

E-ISSN

2073-4409

DOI

10.3390/cells13171495

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