Germline variants at SOHLH2 influence multiple myeloma risk
Germline variants at SOHLH2 influence multiple myeloma risk
About this item
Full title
Author / Creator
Duran-Lozano, Laura , Thorleifsson, Gudmar , Lopez de Lapuente Portilla, Aitzkoa , Niroula, Abhishek , Went, Molly , Thodberg, Malte , Pertesi, Maroulio , Ajore, Ram , Cafaro, Caterina , Olason, Pall I. , Stefansdottir, Lilja , Bragi Walters, G. , Halldorsson, Gisli H. , Turesson, Ingemar , Kaiser, Martin F. , Weinhold, Niels , Abildgaard, Niels , Andersen, Niels Frost , Mellqvist, Ulf-Henrik , Waage, Anders , Juul-Vangsted, Annette , Thorsteinsdottir, Unnur , Hansson, Markus , Houlston, Richard , Rafnar, Thorunn , Stefansson, Kari , Nilsson, Björn , Övriga starka forskningsmiljöer , Faculty of Medicine , Medicinska fakulteten , Strategiska forskningsområden (SFO) , Other Strong Research Environments , StemTherapy: National Initiative on Stem Cells for Regenerative Therapy , LUCC: Lund University Cancer Centre , Department of Laboratory Medicine , WCMM-Wallenberg Centre for Molecular Medicine , Division of Hematology and Clinical Immunology , Avdelningen för hematologi och klinisk immunologi , EpiHealth: Epidemiology for Health , Strategic research areas (SRA) , Hematogenomics , Myeloma research group , Lunds universitet , Myelomgruppen , Profilområden och andra starka forskningsmiljöer , Lund University , Institutionen för laboratoriemedicin , Profile areas and other strong research environments , WCMM- Wallenberg center för molekylär medicinsk forskning and LUCC: Lunds universitets cancercentrum
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Multiple myeloma (MM) is caused by the uncontrolled, clonal expansion of plasma cells. While there is epidemiological evidence for inherited susceptibility, the molecular basis remains incompletely understood. We report a genome-wide association study totalling 5,320 cases and 422,289 controls from four Nordic populations, and find a novel MM risk...
Alternative Titles
Full title
Germline variants at SOHLH2 influence multiple myeloma risk
Authors, Artists and Contributors
Author / Creator
Thorleifsson, Gudmar
Lopez de Lapuente Portilla, Aitzkoa
Niroula, Abhishek
Went, Molly
Thodberg, Malte
Pertesi, Maroulio
Ajore, Ram
Cafaro, Caterina
Olason, Pall I.
Stefansdottir, Lilja
Bragi Walters, G.
Halldorsson, Gisli H.
Turesson, Ingemar
Kaiser, Martin F.
Weinhold, Niels
Abildgaard, Niels
Andersen, Niels Frost
Mellqvist, Ulf-Henrik
Waage, Anders
Juul-Vangsted, Annette
Thorsteinsdottir, Unnur
Hansson, Markus
Houlston, Richard
Rafnar, Thorunn
Stefansson, Kari
Nilsson, Björn
Övriga starka forskningsmiljöer
Faculty of Medicine
Medicinska fakulteten
Strategiska forskningsområden (SFO)
Other Strong Research Environments
StemTherapy: National Initiative on Stem Cells for Regenerative Therapy
LUCC: Lund University Cancer Centre
Department of Laboratory Medicine
WCMM-Wallenberg Centre for Molecular Medicine
Division of Hematology and Clinical Immunology
Avdelningen för hematologi och klinisk immunologi
EpiHealth: Epidemiology for Health
Strategic research areas (SRA)
Hematogenomics
Myeloma research group
Lunds universitet
Myelomgruppen
Profilområden och andra starka forskningsmiljöer
Lund University
Institutionen för laboratoriemedicin
Profile areas and other strong research environments
WCMM- Wallenberg center för molekylär medicinsk forskning
LUCC: Lunds universitets cancercentrum
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_39306bdf64254d54930fcaa0a91e984b
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_39306bdf64254d54930fcaa0a91e984b
Other Identifiers
ISSN
2044-5385
E-ISSN
2044-5385
DOI
10.1038/s41408-021-00468-6
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