Recent Small-Molecule Inhibitors of the p53–MDM2 Protein–Protein Interaction
Recent Small-Molecule Inhibitors of the p53–MDM2 Protein–Protein Interaction
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Publisher
Switzerland: MDPI AG
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Language
English
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Publisher
Switzerland: MDPI AG
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Scope and Contents
Contents
This review presents the last decade of studies on the synthesis of various types of small-molecule inhibitors of the p53– Mouse double minute 2 homolog (MDM2) protein–protein interaction. The main focus is placed on synthetic approaches to such molecules, their cytotoxicity, and MDM2 binding characteristics.
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Full title
Recent Small-Molecule Inhibitors of the p53–MDM2 Protein–Protein Interaction
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TN_cdi_doaj_primary_oai_doaj_org_article_3949f6addb9e4392a54bd7d25c2d3751
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3949f6addb9e4392a54bd7d25c2d3751
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ISSN
1420-3049
E-ISSN
1420-3049
DOI
10.3390/molecules25051211
