Blockade of the JNK Signalling as a Rational Therapeutic Approach to Modulate the Early and Late Ste...
Blockade of the JNK Signalling as a Rational Therapeutic Approach to Modulate the Early and Late Steps of the Inflammatory Cascade in Polymicrobial Sepsis
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Publisher
Cairo, Egypt: Hindawi Limiteds
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Language
English
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Publisher
Cairo, Egypt: Hindawi Limiteds
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Contents
Cecal ligation and puncture (CLP) is an experimental polymicrobial sepsis induced systemic inflammation that leads to acute organ failure. Aim of our study was to evaluate the effects of SP600125, a specific c-Jun NH2-terminal kinase (JNK) inhibitor, to modulate the early and late steps of the inflammatory cascade in a murine model of CLP-induced s...
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Full title
Blockade of the JNK Signalling as a Rational Therapeutic Approach to Modulate the Early and Late Steps of the Inflammatory Cascade in Polymicrobial Sepsis
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TN_cdi_doaj_primary_oai_doaj_org_article_396efeecca2a463a8f355a9bbdef87b5
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_396efeecca2a463a8f355a9bbdef87b5
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ISSN
0962-9351
E-ISSN
1466-1861
DOI
10.1155/2015/591572
