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In vivo assessment of glutamine anaplerosis into the TCA cycle in human pre-malignant and malignant...

In vivo assessment of glutamine anaplerosis into the TCA cycle in human pre-malignant and malignant...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3986ff8f47a14a57a790c10054dc6438

In vivo assessment of glutamine anaplerosis into the TCA cycle in human pre-malignant and malignant clonal plasma cells

About this item

Full title

In vivo assessment of glutamine anaplerosis into the TCA cycle in human pre-malignant and malignant clonal plasma cells

Publisher

England: BioMed Central Ltd

Journal title

Cancer & metabolism, 2020-12, Vol.8 (1), p.29-29, Article 29

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Overexpression of c-Myc is required for the progression of pre-malignant plasma cells in monoclonal gammopathy of undetermined significance (MGUS) to malignant plasma cells in multiple myeloma (MM). c-Myc also increases glutamine anaplerosis into the tricarboxylic acid (TCA) cycle within cancer cells. Whether increased glutamine anaplerosis is asso...

Alternative Titles

Full title

In vivo assessment of glutamine anaplerosis into the TCA cycle in human pre-malignant and malignant clonal plasma cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_3986ff8f47a14a57a790c10054dc6438

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3986ff8f47a14a57a790c10054dc6438

Other Identifiers

ISSN

2049-3002

E-ISSN

2049-3002

DOI

10.1186/s40170-020-00235-4

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