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Synovial mesenchymal progenitor derived aggrecan regulates cartilage homeostasis and endogenous repa...

Synovial mesenchymal progenitor derived aggrecan regulates cartilage homeostasis and endogenous repa...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_39a5e62d9d7a4f7d9e4e3ea507b01586

Synovial mesenchymal progenitor derived aggrecan regulates cartilage homeostasis and endogenous repair capacity

About this item

Full title

Synovial mesenchymal progenitor derived aggrecan regulates cartilage homeostasis and endogenous repair capacity

Publisher

London: Nature Publishing Group UK

Journal title

Cell death & disease, 2022-05, Vol.13 (5), p.470-470, Article 470

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Aggrecan is a critical component of the extracellular matrix of all cartilages. One of the early hallmarks of osteoarthritis (OA) is the loss of aggrecan from articular cartilage followed by degeneration of the tissue. Mesenchymal progenitor cell (MPC) populations in joints, including those in the synovium, have been hypothesized to play a role in...

Alternative Titles

Full title

Synovial mesenchymal progenitor derived aggrecan regulates cartilage homeostasis and endogenous repair capacity

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_39a5e62d9d7a4f7d9e4e3ea507b01586

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_39a5e62d9d7a4f7d9e4e3ea507b01586

Other Identifiers

ISSN

2041-4889

E-ISSN

2041-4889

DOI

10.1038/s41419-022-04919-1

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