Synovial mesenchymal progenitor derived aggrecan regulates cartilage homeostasis and endogenous repa...
Synovial mesenchymal progenitor derived aggrecan regulates cartilage homeostasis and endogenous repair capacity
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Aggrecan is a critical component of the extracellular matrix of all cartilages. One of the early hallmarks of osteoarthritis (OA) is the loss of aggrecan from articular cartilage followed by degeneration of the tissue. Mesenchymal progenitor cell (MPC) populations in joints, including those in the synovium, have been hypothesized to play a role in...
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Synovial mesenchymal progenitor derived aggrecan regulates cartilage homeostasis and endogenous repair capacity
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TN_cdi_doaj_primary_oai_doaj_org_article_39a5e62d9d7a4f7d9e4e3ea507b01586
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_39a5e62d9d7a4f7d9e4e3ea507b01586
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2041-4889
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2041-4889
DOI
10.1038/s41419-022-04919-1