Extension of human GCSF serum half-life by the fusion of albumin binding domain
Extension of human GCSF serum half-life by the fusion of albumin binding domain
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Granulocyte colony stimulating factor (GCSF) can decrease mortality of patients undergo chemotherapy through increasing neutrophil counts. Many strategies have been developed to improve its blood circulating time. Albumin binding domain (ABD) was genetically fused to N-terminal end of GCSF encoding sequence and expressed as cytoplasmic inclusion bo...
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Extension of human GCSF serum half-life by the fusion of albumin binding domain
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TN_cdi_doaj_primary_oai_doaj_org_article_39a6747756f14ee0a4adbf97d46bb10a
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_39a6747756f14ee0a4adbf97d46bb10a
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-021-04560-6