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Epithelial plasticity can generate multi-lineage phenotypes in human and murine bladder cancers

Epithelial plasticity can generate multi-lineage phenotypes in human and murine bladder cancers

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_39bc9eb083864859b7b514bb4bf04fc8

Epithelial plasticity can generate multi-lineage phenotypes in human and murine bladder cancers

About this item

Full title

Epithelial plasticity can generate multi-lineage phenotypes in human and murine bladder cancers

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2020-05, Vol.11 (1), p.2540-16, Article 2540

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Tumor heterogeneity is common in cancer, however recent studies have applied single gene expression signatures to classify bladder cancers into distinct subtypes. Such stratification assumes that a predominant transcriptomic signature is sufficient to predict progression kinetics, patient survival and treatment response. We hypothesize that such st...

Alternative Titles

Full title

Epithelial plasticity can generate multi-lineage phenotypes in human and murine bladder cancers

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_39bc9eb083864859b7b514bb4bf04fc8

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_39bc9eb083864859b7b514bb4bf04fc8

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-020-16162-3

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