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Real-world evidence of the intrinsic limitations of PCR-based EGFR mutation assay in non-small cell...

Real-world evidence of the intrinsic limitations of PCR-based EGFR mutation assay in non-small cell...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_39e8260d6c884d1ba0f6a3c5291782a3

Real-world evidence of the intrinsic limitations of PCR-based EGFR mutation assay in non-small cell lung cancer

About this item

Full title

Real-world evidence of the intrinsic limitations of PCR-based EGFR mutation assay in non-small cell lung cancer

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2022-08, Vol.12 (1), p.13566-13566, Article 13566

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Detection of driver gene mutations is important in advanced NSCLC. The cobas EGFR mutation test is a mutant allele-specific real-time PCR assay with limitation owing to its primer design. Next-generation sequencing-based assay has a higher mutation detection coverage; however, its clinical impact remains unclear. We retrospectively collected the re...

Alternative Titles

Full title

Real-world evidence of the intrinsic limitations of PCR-based EGFR mutation assay in non-small cell lung cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_39e8260d6c884d1ba0f6a3c5291782a3

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_39e8260d6c884d1ba0f6a3c5291782a3

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-022-17394-7

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