Real-world evidence of the intrinsic limitations of PCR-based EGFR mutation assay in non-small cell...
Real-world evidence of the intrinsic limitations of PCR-based EGFR mutation assay in non-small cell lung cancer
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Detection of driver gene mutations is important in advanced NSCLC. The cobas EGFR mutation test is a mutant allele-specific real-time PCR assay with limitation owing to its primer design. Next-generation sequencing-based assay has a higher mutation detection coverage; however, its clinical impact remains unclear. We retrospectively collected the re...
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Real-world evidence of the intrinsic limitations of PCR-based EGFR mutation assay in non-small cell lung cancer
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TN_cdi_doaj_primary_oai_doaj_org_article_39e8260d6c884d1ba0f6a3c5291782a3
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_39e8260d6c884d1ba0f6a3c5291782a3
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-022-17394-7