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Cephalosporin translocation across enterobacterial OmpF and OmpC channels, a filter across the outer...

Cephalosporin translocation across enterobacterial OmpF and OmpC channels, a filter across the outer...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_39f80cd5a3274daa89bec7da2a783110

Cephalosporin translocation across enterobacterial OmpF and OmpC channels, a filter across the outer membrane

About this item

Full title

Cephalosporin translocation across enterobacterial OmpF and OmpC channels, a filter across the outer membrane

Publisher

London: Nature Publishing Group UK

Journal title

Communications biology, 2022-10, Vol.5 (1), p.1059-1059, Article 1059

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Gram-negative porins are the main entry for small hydrophilic molecules. We studied translocation of structurally related cephalosporins, ceftazidime (CAZ), cefotaxime (CTX) and cefepime (FEP). CAZ is highly active on
E. coli
producing OmpF (Outer membrane protein F) but less efficient on cells expressing OmpC (Outer membrane protein C), wher...

Alternative Titles

Full title

Cephalosporin translocation across enterobacterial OmpF and OmpC channels, a filter across the outer membrane

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_39f80cd5a3274daa89bec7da2a783110

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_39f80cd5a3274daa89bec7da2a783110

Other Identifiers

ISSN

2399-3642

E-ISSN

2399-3642

DOI

10.1038/s42003-022-04035-y

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