X chromosome dosage and presence of SRY shape sex-specific differences in DNA methylation at an auto...
X chromosome dosage and presence of SRY shape sex-specific differences in DNA methylation at an autosomal region in human cells
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Author / Creator
Ho, Bianca , Greenlaw, Keelin , Al Tuwaijri, Abeer , Moussette, Sanny , Martínez, Francisco , Giorgio, Elisa , Brusco, Alfredo , Ferrero, Giovanni Battista , Linhares, Natália D , Valadares, Eugênia R , Svartman, Marta , Kalscheuer, Vera M , Rodríguez Criado, Germán , Laprise, Catherine , Greenwood, Celia M T and Naumova, Anna K
Publisher
England: BioMed Central Ltd
Journal title
Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Sexual dimorphism in DNA methylation levels is a recurrent epigenetic feature in different human cell types and has been implicated in predisposition to disease, such as psychiatric and autoimmune disorders. To elucidate the genetic origins of sex-specific DNA methylation, we examined DNA methylation levels in fibroblast cell lines and blood cells...
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Full title
X chromosome dosage and presence of SRY shape sex-specific differences in DNA methylation at an autosomal region in human cells
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TN_cdi_doaj_primary_oai_doaj_org_article_39fc1babb93840e59dac6f833b1dbabe
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_39fc1babb93840e59dac6f833b1dbabe
Other Identifiers
ISSN
2042-6410
E-ISSN
2042-6410
DOI
10.1186/s13293-018-0169-7
