Regorafenib combined with PD1 blockade increases CD8 T-cell infiltration by inducing CXCL10 expressi...
Regorafenib combined with PD1 blockade increases CD8 T-cell infiltration by inducing CXCL10 expression in hepatocellular carcinoma
About this item
Full title
Author / Creator
Shigeta, Kohei , Matsui, Aya , Kikuchi, Hiroto , Klein, Sebastian , Mamessier, Emilie , Chen, Ivy X , Aoki, Shuichi , Kitahara, Shuji , Inoue, Koetsu , Shigeta, Ayako , Hato, Tai , Ramjiawan, Rakesh R , Staiculescu, Daniel , Zopf, Dieter , Fiebig, Lukas , Hobbs, Gabriela S , Quaas, Alexander , Dima, Simona , Popescu, Irinel , Huang, Peigen , Munn, Lance L , Cobbold, Mark , Goyal, Lipika , Zhu, Andrew X , Jain, Rakesh K and Duda, Dan G
Publisher
England: BMJ Publishing Group Ltd
Journal title
Language
English
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Publication information
Publisher
England: BMJ Publishing Group Ltd
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More information
Scope and Contents
Contents
Background and purposeCombining inhibitors of vascular endothelial growth factor and the programmed cell death protein 1 (PD1) pathway has shown efficacy in multiple cancers, but the disease-specific and agent-specific mechanisms of benefit remain unclear. We examined the efficacy and defined the mechanisms of benefit when combining regorafenib (a...
Alternative Titles
Full title
Regorafenib combined with PD1 blockade increases CD8 T-cell infiltration by inducing CXCL10 expression in hepatocellular carcinoma
Authors, Artists and Contributors
Author / Creator
Matsui, Aya
Kikuchi, Hiroto
Klein, Sebastian
Mamessier, Emilie
Chen, Ivy X
Aoki, Shuichi
Kitahara, Shuji
Inoue, Koetsu
Shigeta, Ayako
Hato, Tai
Ramjiawan, Rakesh R
Staiculescu, Daniel
Zopf, Dieter
Fiebig, Lukas
Hobbs, Gabriela S
Quaas, Alexander
Dima, Simona
Popescu, Irinel
Huang, Peigen
Munn, Lance L
Cobbold, Mark
Goyal, Lipika
Zhu, Andrew X
Jain, Rakesh K
Duda, Dan G
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_3a16c10d09a0429d990a0dd5f6981ee3
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3a16c10d09a0429d990a0dd5f6981ee3
Other Identifiers
ISSN
2051-1426
E-ISSN
2051-1426
DOI
10.1136/jitc-2020-001435
