Liquid-liquid phase separation induces pathogenic tau conformations in vitro
Liquid-liquid phase separation induces pathogenic tau conformations in vitro
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Formation of membrane-less organelles via liquid-liquid phase separation is one way cells meet the biological requirement for spatiotemporal regulation of cellular components and reactions. Recently, tau, a protein known for its involvement in Alzheimer’s disease and other tauopathies, was found to undergo liquid–liquid phase separation making it o...
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Liquid-liquid phase separation induces pathogenic tau conformations in vitro
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TN_cdi_doaj_primary_oai_doaj_org_article_3a16f0878afc4de9af28d4f1ab109e2c
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3a16f0878afc4de9af28d4f1ab109e2c
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2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-16580-3