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Liquid-liquid phase separation induces pathogenic tau conformations in vitro

Liquid-liquid phase separation induces pathogenic tau conformations in vitro

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3a16f0878afc4de9af28d4f1ab109e2c

Liquid-liquid phase separation induces pathogenic tau conformations in vitro

About this item

Full title

Liquid-liquid phase separation induces pathogenic tau conformations in vitro

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2020-06, Vol.11 (1), p.2809-16, Article 2809

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Formation of membrane-less organelles via liquid-liquid phase separation is one way cells meet the biological requirement for spatiotemporal regulation of cellular components and reactions. Recently, tau, a protein known for its involvement in Alzheimer’s disease and other tauopathies, was found to undergo liquid–liquid phase separation making it o...

Alternative Titles

Full title

Liquid-liquid phase separation induces pathogenic tau conformations in vitro

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_3a16f0878afc4de9af28d4f1ab109e2c

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3a16f0878afc4de9af28d4f1ab109e2c

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-020-16580-3

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