ASCL1 phosphorylation and ID2 upregulation are roadblocks to glioblastoma stem cell differentiation
ASCL1 phosphorylation and ID2 upregulation are roadblocks to glioblastoma stem cell differentiation
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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The growth of glioblastoma (GBM), one of the deadliest adult cancers, is fuelled by a subpopulation of stem/progenitor cells, which are thought to be the source of resistance and relapse after treatment. Re-engagement of a latent capacity of these cells to re-enter a trajectory resulting in cell differentiation is a potential new therapeutic approa...
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Full title
ASCL1 phosphorylation and ID2 upregulation are roadblocks to glioblastoma stem cell differentiation
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TN_cdi_doaj_primary_oai_doaj_org_article_3a17aa5949194929914e94610039108c
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3a17aa5949194929914e94610039108c
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-022-06248-x
