Inhibition of the protective effects of preconditioning in ischemia–reperfusion injury by chronic me...
Inhibition of the protective effects of preconditioning in ischemia–reperfusion injury by chronic methadone: the role of pAkt and pSTAT3
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Cardiac ischemic preconditioning (Pre) reduces cardiac ischemia–reperfusion injury (IRI) by stimulating opioid receptors. Chronic use of opioids can alter the signaling pathways. We investigated the effects of chronic methadone use on IRI and Pre. The experiments were performed on isolated hearts of male Wistar rats in four groups: IRI, Methadone +...
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Inhibition of the protective effects of preconditioning in ischemia–reperfusion injury by chronic methadone: the role of pAkt and pSTAT3
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TN_cdi_doaj_primary_oai_doaj_org_article_3a2543b7e19e4aee82850f1634734b17
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3a2543b7e19e4aee82850f1634734b17
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-024-65349-x
