miR-497-5p/SALL4 axis promotes stemness phenotype of choriocarcinoma and forms a feedback loop with...
miR-497-5p/SALL4 axis promotes stemness phenotype of choriocarcinoma and forms a feedback loop with DNMT-mediated epigenetic regulation
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Author / Creator
Peng, Zheng , Zhang, Yi , Shi, Dazun , Jia, Yanyan , Shi, Huirong and Liu, Huining
Publisher
London: Nature Publishing Group UK
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Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Contents
Choriocarcinoma stem-like cells (CSLCs) might be at the origin of choriocarcinoma development associated with drug resistance or relapse. Spalt-like transcription factor 4 (SALL4), which is considered to be a stemness-related gene, can be regulated by miRNAs. In this study, SALL4 result is associated with progression-free survival of choriocarcinom...
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Full title
miR-497-5p/SALL4 axis promotes stemness phenotype of choriocarcinoma and forms a feedback loop with DNMT-mediated epigenetic regulation
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TN_cdi_doaj_primary_oai_doaj_org_article_3a93796482c84d1591f5636e656f0834
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3a93796482c84d1591f5636e656f0834
Other Identifiers
ISSN
2041-4889
E-ISSN
2041-4889
DOI
10.1038/s41419-021-04315-1
